Agenerase, also known as Amprenavir, is a protease inhibitor approved for use in children age four and older and in adults in combination with other antiretrovirals for HIV infection. Agenerase works by decreasing the viral load (the amount of virus circulating in plasma) and increasing CD4 cell counts (the measure of immune cells created by the body) in users. The drug is not a cure for HIV infection. Patients may continue to develop infections and other complications associated with HIV disease. The long-term effects of Agenerase, made by GlaxoSmithKline, are not known at this time. The U.S. Food and Drug Administration (FDA) approved Agenerase in 1999.

Possible side effects of Agenerase use include, but may not be limited to, skin rash, nausea, vomiting, diarrhea and a tingling sensation in the mouth. Agenerase has also been linked to severe and life-threatening skin reactions, including Stevens-Johnson syndrome.

A black box warning indicates that the medication is contraindicated in infants and children below the age of 4 years, patients with renal or hepatic failure, pregnant women and patients treated with disulfiram or metronidazole. Agenerase oral solution should only be used when capsules or other protease inhibitors are not an option.

See your doctor if you have experienced an adverse reaction after being administered Agenerase. In addition, it may be important to contact an attorney who can help you protect your legal rights. Please keep in mind that there may be time limits within which you must commence suit.



See Also

  1. HIV & AIDS Drugs: Overview
  2. Diarrhea: Overview
  3. Nausea: Overview
  4. Stevens-Johnson Syndrome / Erythema Multiforme
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